People who defended Conor's loss against Khabib used the argument that Mcgregor was already rich at the time and wasn't motivated, and stated that "Motivated McGregor" would destroy Khabib. People were so amused by this that they started using the term as a joke to mock McGregor fans, often using the term to describe McGregor in an almost Godlike way.
In terms of Presidential Candidacy, motivation and public endorsement is endowed with in the person to spread their message and make themselves and others vote.