gay slang, pre-Stonewall era, meant as a put-down. Meaning there's too much powder make-up on your powder puff, Mary; you need to tone it down. You need to calm down.
Feel better you got that out of your system? Go fluff your puff.
Advertised by Homestar Runner, who eats about 147 of them with a "tall glass of melonade!" (or marmalade). It's mascot is a big white marshmellow called Marshie (thats M, then arshie!). Not to be confused with "Flushy Push Marshmellows", "Fluffity Puffity Marshalades" or "Fluffy Puffies".
Homestar: "Before I drink a tall glass of melonade, I like to eat about 147 FLUSHY PUSH MARSHMELLOWS! Seriously folks..."
Director: "Cut! You said Flushy Push."
Homestar: "I know! Can you believe it?!?!"
Director: "They're called Fluffy Puff."
Homestar: "I know! Can you believe it?!?!"
"Before I drink something, often times I eat something too!"
"Before I drink a tall slice or marmalade I eat 147 marshmellows. I mean fluffy puffies."