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Name for the worst people in existence, also name for vagina or something thats broken.
Duff: "My name is @##$ Duffus"
Bystandard: "How do you sleep at night"
duffus by Patrick!@#$%%^^ April 28, 2006
A long, thick, uncircumcised penis; The best sex any member of the female species could hope for.
That guy had quite the duffus!

I had some duffus last night..... it was phenomenal!
Duffus by imsothug May 22, 2011
To absolutely fucking murk a mans with your bare mitts.
Mi yute I’m bouta straight duffus this mandem ahlieeee.
Duffus by Macdaddy93 June 28, 2018

duffus fuck 

a duffus fuck is a fella who is a complete dumb shit in life and don't know how to react to being called duffus fuck
duffus fuck by duffusfuck April 14, 2017

muffus duffus 

A politically correct way of saying "mother fucker"
Get over here and clean up your mess, muffus duffus!
muffus duffus by ONPS January 30, 2008

Rufus Poofus Mc.Duffus 

This is a girl or boy who fakes his LGBTQ identity to get into sleepovers of the opposite sex and perv on them.
Person A:Did you here about that time Jamal lied about being gay to get into Vicky’s sleepover?

Person B: OMG what a Rufus Poofus Mc.duffus