A temporary loss of judgment and higher reasoning capability that one may experience immediately after consumption of KFC's double-down sandwich. Initial symptoms may include confusion, euphoria, and slurred speech. These are soon followed by loss of physical coordination and language ability (several patients have been observed to repeatedly utter variations of the phrase "hurr herp derp"). Patients may then enter a trance-like state for prolonged, variable amounts of time. A full recovery is typical within a few hours to a few days, although in some cases lasting brain damage has been reported.
In the hospital, it was discovered that what psychiatrists initially believed to be severe mental retardation was nothing more than a case of Double Down Syndrome after a late lunch.
by theloniius April 13, 2010
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The listless state of consciousness experienced after eating a KFC Double Down sandwich.
Brad: "Why does Ken look like he's about to collapse?"

Trevor: "Judging by the lunch we just ate, it is my determination that Ken is suffering from Double Down Syndrome."
by Lamb Lamb April 17, 2010
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A sickness developed while playing Blackjack that causes you to risk all your chips constantly from doubling down.
Jim lost all of his money at the casino yesterday after getting a case of Double Down's Syndrome.
by Bob The Larry July 11, 2011
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When someone has twice the effects of down syndrome, (only reach 2 feet tall, and only live to the age of 20) , and they always double down. They are very poor with money, and are not very good at gambling.
"Man we kicked that midget's ass last night in the club at Hold 'em"
"Yea I know, he musta had double-down syndrome or somthin'; he never could go a hand without double-down'. "
by 17link7 December 31, 2015
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