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Verb; to handle a situation, mostly negative situations, in the most efficient, graceful and ruthlessly badass way possible to ensure the best outcome for oneself and the worst outcome for one's enemies. Slang: to treat women like disposable objects for sexual pleasure.
"You're going to drop me, Lucky Strike? That's fine, I'll just Don Draper your ass with a full page add in the paper."

"That Megan secretary is so hot, I'mma Don Draper THAT!"
by DouchebagGalore August 24, 2011
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Bad motherfucking ad man from the show Mad Men. Enjoys such pastimes as drinking scotch at work, making chauvinistic comments to women, and getting laid whenever he pleases. An American icon.
Yo, I got myself a new "WWDDD" bracelet, so whenever I'm unsure I can ask myself What Would Don Draper Do? and it's all good.
by slevin_123 December 12, 2008
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