Verb; to handle a situation, mostly negative situations, in the most efficient, graceful and ruthlessly badass way possible to ensure the best outcome for oneself and the worst outcome for one's enemies. Slang: to treat women like disposable objects for sexual pleasure.
"You're going to drop me, Lucky Strike? That's fine, I'll just Don Draper your ass with a full page add in the paper."
"That Megan secretary is so hot, I'mma Don Draper THAT!"
"That Megan secretary is so hot, I'mma Don Draper THAT!"
by DouchebagGalore August 24, 2011