Bro-sis 

a sister (usually biological) who is also a bro, displaying all or some of the characteristics of a bro.

Not to be confused with brosis which is an infectious disease.

My sister is totally a bro-sis.

Last night my bro-sis had a party at which she wore a polo shirt, drank beer from a red plastic cup, and shouted "WHOOOO" loudly several times.

Bro-sis by Leonardaturtle March 10, 2011

Bro-sis 

Where a male sasly takes the brother approach, whilst strategically planting the seeds of love in the otherwise oblivious "sister" victim, and allows 14 years to pass before finally reaping the produce of a perfectly sown seed.

i think hes on a bro-sis ting bruv, you no say hes on it

Bro-sis by The Bricklayer September 16, 2007

Bro / Sis 

Have you wondered why you are being called bro? and sister? well its time to know buddy!

this is how Bro And SIster is used as a sentence For Example if you don't know this Then How would you define Bro / Sis
Hey bro! for example that means Hey Brother

and now the sis for example =
Hey Sis! That means Hey Sister meaning his sister

Bro / Sis by alou2a14 August 27, 2023

Bro or Sis 

Bro or Sis is usually used in chat rooms in Omegle. Its asking if you are female or male.

Are you a bro or sis?

Bro or Sis by PukeOnMe December 25, 2015

Sis Vs Bro 

A trash ass channel with a girl and a boy that like to brag about useless shit like their Iphone X's and if you hate about them,then a fan of them would most likely would say "Rude" since they can't fucking expand their vocabulary.

When I think of greedy,I think of Sis Vs Bro

Sis Vs Bro by MrFortnite June 15, 2018

Sis vs Bro 

An absolutely retarded channel that no one over the age of 10 watches unless you are mentally retarded and like having your ears bleed. If you say they suck or you hate them a fan will say "That's mean!" because they are younger than 10.

"Man, I caught my 9 year-old sister watching that fucking stupid channel Sis vs Bro. They make my ears bleed."
"Really bro? Man that sucks. Now your sister has got to be disowned "

Sis vs Bro by singularworld September 28, 2019

sis vs bro 

my most favourite YouTube channel in the whole entire world they specialize in gaming videos and loads of different wacky challenges. they are amazing people and were lucky to have them on the internet.

lots of love jasmine m

sis vs bro are the best youtubers alive

sis vs bro by jazzylimitlessgamer January 12, 2021