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1. Said after someone says something that may be considered gay or suspect.

2. Something that looks suspect or gay.

3. Another way of saying "no homo"
Guy 1: "Man I sure could go for a hot dog right now, I'm not where the craving came from. It just kind of came in my mouth"

Guy 2: "AYO!!"
Ayo!! by Auspicious June 21, 2008
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when your homie says something sus
friend 1: yo u looking mad cute can i give head
friend: 2 ayo wtf
Ayo by JULIan KOyy >:D October 26, 2020
A response to when someone says something suspicious "sus" or inappropriate related.
- Bro I want to smack her booty cheecks

-aYO
ayo by bruhos April 11, 2022
Someone who says "AYO" just recently heard a sus or dirty comment.
Friend: I have a big di*k
You: AYO
Ayo by ewpersonlmao March 6, 2022
It means Hey You.
It is mainly used when addressing an individual in any given situation to get his or her attention.
Ayo! What time is it?
Ayo, Can I talk to you for a minute?
Ayo by E520 October 22, 2003
Just calling somebody out if you don't know their name.
Or expressing how dumb that action was.
Or telling people how cool the action or thing you're seeing is.
Ayo! Bring yo bitch ass here!

Ayo cmon dawg. that shit was dumb as fuck

AYOOOOOOO THAT SHIT WAS LIT ON THE DEAD HOMIES
Ayo by wowloserluffy September 24, 2020
Slang for "hey, yo."
"Ayo, turn down the volume, a'ight?"
Ayo by rc8s March 14, 2022