Top definition
It means Hey You.
It is mainly used when addressing an individual in any given situation to get his or her attention.
Ayo! What time is it?
Ayo, Can I talk to you for a minute?
by E520 October 22, 2003
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2
a streamlined fusion of the salutation "hey, yo" that goes over extremely well with the modern urban entrepreneur.
"ayo, slim, whatcha'll be on?"
by sinicalypse May 04, 2003
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4
Someone everyone wants to be cause he's sick at everything
by Asssssssas November 07, 2016
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5
a response for a very suspect or homosexual comment.
Dude 1: That's a big bulge in your pants, what is it?

Dude 2: AYOOOOOOO!!!!!!!!!!!!!
by Sosa Ave July 13, 2008
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6
This is a Nigerian name of the Yoruba dialect which means 'Joy'. It can be combined with other names.
e.g. Ayodele meaning Joy (Ayo) has come/arrived home (Dele)
by nun ur biznaess September 03, 2006
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7
The best song ever by Andre Nickatina. Ayo for Yayo is a tale..all about that yayo...
AYO FOR YAYO WALK AROUND WITH YAYO ALL IN MY NASAL I MUSTA BEEN CRAZED YO... damn boyyy that's my favorite jam! -Rick aka..crackbat.
by girlonthestreet March 31, 2004
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