It means Hey You.
It is mainly used when addressing an individual in any given situation to get his or her attention.

a streamlined fusion of the salutation "hey, yo" that goes over extremely well with the modern urban entrepreneur.

Ayo is an amazing he has an amazing heart that can heal any wounds. He is a person that will do anything to help you and bring you back on track. He may not be the Handsome person everyone thinks of but he has a handsome heart. He also could look weak but he his a strong person emotionally and Physically so don’t mess with him he comes from a rich family and normally a person from Africa. In Yoruba his name means joy. And he definitely brings joy to peoples hearts and lives. Ayo is definitely a person you can confine in. He will have your best interest in heart.

often used as a gteeting in replacement of "hey yo"

a response for a very suspect or homosexual comment.

This is a Nigerian name of the Yoruba dialect which means 'Joy'. It can be combined with other names.

Someone everyone wants to be cause he's sick at everything