Ayo 

when your homie says something sus

friend 1: yo u looking mad cute can i give head
friend: 2 ayo wtf

Ayo by JULIan KOyy >:D October 26, 2020

ayo 

A response to when someone says something suspicious "sus" or inappropriate related.

- Bro I want to smack her booty cheecks

-aYO

ayo by bruhos April 11, 2022

Ayo 

Someone who says "AYO" just recently heard a sus or dirty comment.

Friend: I have a big di*k
You: AYO

Ayo by ewpersonlmao March 6, 2022

Ayo 

It means Hey You.
It is mainly used when addressing an individual in any given situation to get his or her attention.

Ayo! What time is it?
Ayo, Can I talk to you for a minute?

Ayo by E520 October 22, 2003

Ayo 

Just calling somebody out if you don't know their name.
Or expressing how dumb that action was.
Or telling people how cool the action or thing you're seeing is.

Ayo! Bring yo bitch ass here!

Ayo cmon dawg. that shit was dumb as fuck

AYOOOOOOO THAT SHIT WAS LIT ON THE DEAD HOMIES

Ayo by wowloserluffy September 24, 2020

Ayo 

Slang for "hey, yo."

"Ayo, turn down the volume, a'ight?"

Ayo by rc8s March 14, 2022

ayo 

a streamlined fusion of the salutation "hey, yo" that goes over extremely well with the modern urban entrepreneur.

"ayo, slim, whatcha'll be on?"

ayo by sinicalypse May 4, 2003