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1) Stands for what the fuck is up?

2) A commercial trying to inform people about "Big Tobacco's crazy ways and addictive products"
whudafxup with that!?

WOW, I love that whudafxup commercial!
whudafxup by bockz April 16, 2007
Words you can keep
slang that is used to mean "what the fuck is up?"
is also an anti-tobacco ad capaignhttp://www.whudafxup.com/
shelly.. whudafxup w/that?
whudafxup by dfhdfh September 3, 2008
Related Words
The lamest, stupidest, gayest commercials about cigarettes.
Whudafxup is a gay commercial.
whudafxup by BigZaccyStyle September 15, 2006
a clever way to say "what the fucks up" without actually cursing.
"whudafxup with that shirt? its so ugly!"
whudafxup by rachiebear! October 20, 2006
What a F*** up!! ie bonehead
There is no "is" in whudafxup, figure it out people.
whudafxup by scamp13 February 7, 2008

wadafxup 

An apostrophe-less contraction (or word amalgam) meaning "What the fuck is up?" Started by truth.com's PSA campaign.
"Hey, did you hear that Jill is dating Johnny now?"

"Yeah, wadafxup with that?"
wadafxup by Mr.Melon October 5, 2008
Meaning: What the fucks up?
Started from the Truth commercials that are against the tobacco companies.
Tobacco companies compared the addictivness of nicotine to jogging and m&m's. Whadafxup?
whadafxup by Alk3 Ownz U July 31, 2006
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There are no hot girls in the area, theres only satellite baddies.
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