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Idiotic anti-tobacco propaganda which uses scare tactics and idiot comparisons to spread irrational fears about tobacco. Hosted by some jackass who looks like he showers once a year and aspires to look as much like an insect as possible with his clothes and glasses.
went to a gun store to ask for light bullets, whadafxup?
whadafxup by robbles August 23, 2007

wadafxup 

An apostrophe-less contraction (or word amalgam) meaning "What the fuck is up?" Started by truth.com's PSA campaign.
"Hey, did you hear that Jill is dating Johnny now?"

"Yeah, wadafxup with that?"
wadafxup by Mr.Melon October 5, 2008
1) Stands for what the fuck is up?

2) A commercial trying to inform people about "Big Tobacco's crazy ways and addictive products"
whudafxup with that!?

WOW, I love that whudafxup commercial!
whudafxup by bockz April 16, 2007

whuddafxup? 

Slang for "What The Fuck Is Up?"
But, it sounds cooler.
lolz.
Gina kissing a girl.
Mariah walks in.
Mariah- "whuddafxup? WHUDDAFXUP?!?!?!?!"
Gina- "I'm so sorry............."
whuddafxup? by MariahGina March 25, 2007
slang that is used to mean "what the fuck is up?"
is also an anti-tobacco ad capaignhttp://www.whudafxup.com/
shelly.. whudafxup w/that?
whudafxup by dfhdfh September 3, 2008

Whadafuck 

Exclamatory remark expressing confusion over or about something. Only to be used when slightly aggravated or agitated.
Somebody dents your car.
"Whadafuck!"
Whadafuck by Joe RS August 4, 2007