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Meaning: What the fucks up?
Started from the Truth commercials that are against the tobacco companies.
Tobacco companies compared the addictivness of nicotine to jogging and m&m's. Whadafxup?
whadafxup by Alk3 Ownz U July 31, 2006
Related Words
Idiotic anti-tobacco propaganda which uses scare tactics and idiot comparisons to spread irrational fears about tobacco. Hosted by some jackass who looks like he showers once a year and aspires to look as much like an insect as possible with his clothes and glasses.
went to a gun store to ask for light bullets, whadafxup?
whadafxup by robbles August 23, 2007
A morph of the phrase "What the f*ck is up?".
Ileena: Get awat form me skank!

Elisha: Wadafuxup with you today?!
wadafuxup by (Enter name here) March 13, 2008