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uh-oh spaghetti-o's 

An exclamation made after the realization one has fucked up beyond repair.
Dude, I just shot your mom! Uh-oh Spaghetti-oh's

uh-oh spaghetti-o's 

(N.) Homer Simpson's (II) Catch phrase in the short-lived Fox Dramedy, "Police Cops." Originally, a suave, stereotypical Policeman, Homer Simpson (II) was retooled into a fat, bumbling, Chris-Farley-esque doofus, who's catchphrase was always "Uh-Oh-Spaghetti-O's!" which was taken from the pasta of the same name.
Homer: "I just helped out in the Toys-for-Guns program."
Chief: "Homer! It's Guns-For-Toys!"
Homer: "Uh-oh spaghetti-o's"
uh-oh spaghetti-o's by G-Union November 25, 2003

uh-oh spaghetti-o's 

cop: "Sir are there any drugs or any weapons ion your vehicle that I should know about?"
me: "No sir!"
cop: "HOLY SHIT there is over 10 punds of weed in your trunk"
me: "uh-oh spaghetti-o's!!!"
uh-oh spaghetti-o's by MetalHead November 23, 2004

uh oh spaghetti o's 

usually when something goes wrong or you just started having drunken sex to realise its your sister!
"i think ive caught my scrote in my zipper " "uh oh spaghetti o's"!

Uh-oh spaghetti-os 

A term used by a friend or affiliate of a person who propagates some sort of trouble, using this term is a last-resort where trouble is imminent and realistically is never used by the perpetrator receiving the outcome of his wrong-doing, mishap or misdemeanor on the flip side.

May also be substituted for spaghetti-hoes when a skanky skiny broad trundles past.
Example 1, of Uh-oh spaghetti-os:

Person 1: Why is that jock steam-rolling in our
direction, he's striding like we're the feast after his
fasting.

Person 2: Well I got his dumb ass broad into bed and left
my calling card.

Person 1: Well what's that?

Person 2: Haven't you heard what they say about me? They
call me the nerd with the brain in his wingless, NOT
skinless larger than your average sea bird plane.

Person 1: Well *gulp*, which spot should we present him
with to beat on?

Person 2: Well, *points to spot and lifts shirt up a
slight amount* I think I have a slight slip disc just
above my pelvis; thing's been killin' me; maybe he can
thump it back into position.

Person 1: Right... is it to late to refer back to the old
wrongly timed but always brilliantly quipped phrase Uh-oh
spaghetti-os in such times of imminent trouble?

Person 2: It would appear that way.

Example 2:

"Look at that thin piece of spaghetti figured ass" said Wanda."I
could curl that scrawny length of disgrace right into a pasta shell." She went on: "I
mean you don't see black spaghetti hoes like that
none-too-often. Must be hard for her to find a partner,
must need a man build like the graphite in a pencil -
aye aint your Ray the perfect fit!?". "Yeah!?" retorted Donna with an on the sly tinge of surprise on her breath after hearing the sardonic remarks of her portly pal, "Wanda, you could also use her as a tooth-pick what with that 15 centimeter gap hanging between those prominent front teeth o' yours."

You must understand I'd been listening to sir Mixalot - that's why I used black people as an example, in no way racist here people. Hope that was received with chuckles and not raised knuckles.

uh-oh spaghetti-o's 

"oh shit"
term borrowed from the late 1970's-ish commercial jingle for franco-american's spaghetti-o's
*camera shows to hippies smoking weed*
dude. we just smoked 2 bowls. i am starving. what do we have to eat?
*cue annoying jingle*
uh-oh, spaghetti-o's
franco-american
*camera shows 2 confused gentlemen having just heard said jingle who now smile, realizing they have canned "spaghetti" to eat*
sweet!
*and fade to black*
uh-oh spaghetti-o's by mr pink November 18, 2004
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