Normally used by Destiel shippers as a play on a famous fanfiction called Twist and Shout.
Because of how sad the fic is, many feel their heart is ripped from their chest.
When you scroll down your twitter timeline and see a very attractive person's "twit pic" and you click on their profile to get a better look at them, to come to find that they are not as "Attractive" as they looked from your timeline.
Boy 1 (on twitter): Oh wow she's kinda cute.
Boy 2: Yeah she looks halfway decent.
Boy 1 *clicks on profile*: Twit pic fake out.