Derived from Star Wars in which various characters use the line to describe someone as powerful in the Force. Also used to describe someone with a very valuable ability and/or talent that is innate and unlearned as opposed to something worked at or achieved by effort.
From American Pie 2:
(Oz accidentally runs into a bunch of women, and they follow him back to a formerly sausage fest party)
Jim: Incredible.
Stifler: (Nodding) The Force is strong in him.
Short-hand for the word floccinaucinihilipilification, meaning the estimation of something as valueless (encountered mainly as an example of one of the longest words in the English language).
Precedes or follows either a gratuitously disrespectful or honest remark, originated in New York City. Used in similar fashion to "no offense" or "to be honest," interchangeably.
Ya mans is wild buns, respectfully. Respectfully he's washed.
After school, The Modells on Jamaica Ave was active. Respectfully.