rustled my jimmies

as others have stated: something has angered, upset, annoyed, aroused you
this is more of a side note on origin - I suspect the phrase was a spontaneous misquote of a line from the Weezer song "Say It Ain't So" ("...flip on the telly/ wrestle with Jimmy...")

man, that pic was disgusting.
yeah, that one rustled my jimmies

rustled my jimmies by kingprout1 September 2, 2015

Rustle My Jimmies 

“That Really Rustled My Jimmies” is an expression that is used to convey feelings of discontent or discomfort in response to someone else’s post in imageboards and discussion forums, most notably on 4chan. To rustle one's jimmies means to make someone discontent or to bother someone.

Man 1: "This guy is your boyfriend? He's worthless!"

Man 2: "That really does Rustle My Jimmies man..."

Rustle My Jimmies by Carlos-a-16 December 12, 2012

rustles my jimmies 

When something rustles your jimmies, it annoyed you or made you slightly angry.

Person 1: I can't believe Chipotle ran out of black beans!
Person 2: I know! That really rustles my jimmies.

rustles my jimmies by the only frito left in the bag June 4, 2018

Rustle My Jimmies 

Repositioning sexual organs. For males, repositioning of the penis and testicles. For females, repositioning of the breasts.

In awkward situations I like to rustle my jimmies

Rustle My Jimmies by Skewesy October 20, 2013

Russled my jimmies 

To frustrate or annoy someone

"They way Barbra acted really russled my jimmies!"

Russled my jimmies by nayernay June 3, 2018