Commonly used in phrases that induce spasms of retardation, which eventually lead to an onslaught of complete and utter gayness, and worse - gangsterism.
michelle p.: Like oohh mee geee! That was awesomeness to the maxhouseness, like cyeh!~
Modifying the word "inhouse" where you only play with people you know in the game called Heroes of Newerth, manhouse is the same but the game mode is All pick, auto balanced, all random, no swap, no re pick.
It is called manhouses because you play what you get and prove that you are a man.