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Manopause 

A time when a man's chemical balance becomes shifted and he has a breakdown and/or becomes an asshole. Symptoms include- Irritability, mood swings, thoughts of suicide, depression, over sensitivity, paranoia, and feelings of helplessness.
When Mike turned 50, his manopause kicked in and he bought a Corvette and then drove it off a cliff.
Manopause by Woodbilly May 14, 2011

Manopause 

A sad period of time in a married man's life when he simply doesn't get any action from the wife and is essentially (paused). This usually (though not specifically) occurs in middle age. But depending on the situation can occur at any point in time if the man is not careful.

Sadly (assuming sad..) the married 'manopaused' man therefore has no choice but to seek alternative sources of extra marital fulfillment, if successful he becomes (un-paused) but is now in serious risk of extreme excitement resulting in vastly improved looks, healthier eating, great ideas, amazing productivity, and general 'teenage' like behavior after which then carries the risk of 'getting caught'. Assuming he even has the confidence to even dare to attempt this bold move in the first place the first section of this applies. If not then,

He simply accepts he is 'manopaused', and lives the life of a eunuch
"Ah man, look at that dude over there, he looks so pent up, he must be manopaused, I sure hope he went with option 1 :)"

"I saw a dude today in the supermarket, I could just tell by all those shopping bags he had been manopaused.. I saw option 2 written all over him"
Manopause by Bigabongo June 11, 2020

Manopause 

A mental condition typically found in men in their mid to late 50's brought on by the realization that old age is just around the corner. Symptoms include: frequent reminiscing about the “good ol’ days”, cranky judgmental attitude and a closed minded approach to anything new. Usually punctuated by the chronic need to play a lot golf and vote republican. The condition is difficult to cure and almost always progresses into oldtimers disease.
"Get off my lawn!" Mr. Wagner screamed at the kids playing next door. What happend to him? they asked each other, one kid whispered "my mom says he's got manopause"
Manopause by Paul Lowry April 16, 2006

bipolar menopausal bitch (bpmb) 

any older woman who changes from second to second her attitude, feelings, and temperament towards any given issue and then makes up completely unrelated issues to validate herself.
You: I have a problem with rumors about me being spread about me what can I do?
Her: Well its all your fault they think what they do. You control what other people think! The Kitties always come first!? I am having a bad day is it hot in here??
You: What are you talking about are you some kind of bipolar menopausal bitch (bpmb)?
Her: What did you say???

menopausal mafia

needy, sexually frustrated women of a certain age who comprise the internet posse devoted to stalking UK X Factor flop Matt Cardle and luring him into their sheds
Now that Cardle has been dropped by his record company and has time on his hands, every one of the menopausal mafia will be flicking her bean more furiously than ever.
menopausal mafia by FattyEms November 9, 2012

Manopause 

A psychological condition in which a man in his mid to late 50s appears to have lost his mind and drives everyone around him insane with his crabbiness, irrationality, and flash temper. He may exhibit a "blame everyone else" approach when he is in the wrong. He may exhibit opinions that are completely opposite to what he used to have (ie. voting republican when he was a life long democrat or becoming a male chauvenistic pig when he always support women's liberation.)
"Mom, Dad just yelled at me for taking out the garbage. He said I was doing it wrong and got irrationally angry," said the teenaged daughter. "Yeah, he's in Manopause. Nothing he does makes sense anymore," said the mom.
Manopause by Daiseyheadmaisey August 5, 2008