Sort of like "you do you," but with a strong implication that you're talking out of your ass. Basically "you're an idiot and what you're saying is stupid, if you want to keep going I guess I won't stop you."
Bob: "The world is run by lizard people."

Sue: "There's no such thing as lizard people, but go off, I guess."
by Mai Ainsel July 1, 2020
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When someone is proven to be wrong/stupid/lying, but you'll entertain them anyway.
You know we didn't sleep together, but go off I guess.
by Scratch 'N Sniff Asshole March 4, 2021
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you say this when your friend says something that proves you were wrong, but you don't want to admit it.
Gasinah: The answer to the math problem is 26, your paper says the answer is 76. you are stupid.

Jaakawbie: go off i guess
by mckenzielovesgrapes March 16, 2019
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