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gankles are what happens when cankles get out of control.

basically the "gunt" and the "cankles" merge into a larger more menacing form of fatness called "gankles"...

expressed mathmatically it is:

(gut + cunt) + (calf + ankles) = gankles
dude, what the hell happened to her? i mean she used to be not bad with just cankles but now she's got gankles for god's sake! her lower body has become one huge continuous set of gankles!
gankles by stoneyface December 5, 2009
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glankles 

a compound of the words "glass", "ankles". This term describes painful or injured ankles due to infirmity or misadventure.

This term is often used used when a person receives ground-shock when jumping down from something, when an athlete becomes injured from landing on their foot poorly, or in video gaming, where a player's character takes unexpected "fall damage".

The term is similar to "grankles"; infirmity of ankles, and subsequent difficulty walking, due to frailty of advanced age.
"Just jump down, the fence isn't that high!"
"Arrrgh, my glankles!.. no really.. I think I twisted something.."

"She has been sidelined for 3 games because of a recurrent injury. The team is hoping those glankles don't cost them the Cup."
glankles by Erebus February 2, 2019

ganklebanker 

A person who masturbates, and ejaculates in their own hands. Immediately after ejaculation, they commence random hand shakes with people around their office, or place of work.
I was planning on quitting my job this week, so I ganklebanked my boss and I think he wiped it off on his face.
ganklebanker by Rukorogneo April 21, 2005
Any form of gastrointestinal distress including bloating, gurgles, cramps, turtle pops, short shits, or diarrhea.
"I need a shitter quick, I've got the Gangles."
Gangles by BOTWN September 12, 2021

Gunklesnizer 

a gunklesnizer is a word that only the creators will know the true meaning. This will be a urban laegend forever
your such a gunklesnizer!
When you gank (thrash) the shit out of your ankle, it becomes a gankle.
Did you see that dude's gankle? It was all jacked up
gankle by Febtober Jackson November 1, 2011

ganklesaurus funkle 

a prefix to something that is funky, crooked, twisted, stained, malformed, repulsive, odorous, inappropriate, alarming, calloused, disturbing,
I hate when old men wear sandals and let their "ganklesaurus funkletoes" show!

If you do not brush your teeth and floss regularly you could end up with "ganklesaurus funkleteeth"

The last thing anyone wants to see is some nasty woman's "ganklesaurus funklebutt" hanging out of the bottom of a too short skirt