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Dharmageddon 

Term used to describe the big explosion at the end of Season 5 of the TV show "Lost" in which (apparently) everyone in the Dharma Initiative was destroyed by the detonation of a nuclear bomb.

Can also be used to refer to the upcoming Season Finale of "Lost" - the final end of the show which remains to be seen.
Dude, check out this blog, it's got spoilers on what happened to all the characters after the Dharmageddon last year.
Dharmageddon by Peter Lorre January 12, 2010
Related Words

dogmageddon

Catastrophe brought about by an authority figure declaring a set of principles and/or beliefs as inconvertibly true
The President caused a nationwide dogmageddon in the year 2020
dogmageddon by bitsyblanket September 19, 2020

datageddon

When a company gets hacked and IT is forced to shut down systems, networks, and data access to contain the breach, bringing normal operations to a sudden halt. Often accompanied by panic emails, locked accounts, and employees realizing how dependent everything is on data systems.
Email is down, the network drives are offline, and IT just told everyone to disconnect from Wi-Fi — welcome to datageddon.
datageddon by Munchieman5150 March 9, 2026

Ramageddon

The term to describe the sudden increase in RAM prices due to corporations buying it all for their AI shite like Microsoft.
Ramageddon is happening, thanks a lot Microsoft, google and everyone else for buying all our ram and shoving your AI shite up our asses.