Top definition
Term used to describe the big explosion at the end of Season 5 of the TV show "Lost" in which (apparently) everyone in the Dharma Initiative was destroyed by the detonation of a nuclear bomb.

Can also be used to refer to the upcoming Season Finale of "Lost" - the final end of the show which remains to be seen.
Dude, check out this blog, it's got spoilers on what happened to all the characters after the Dharmageddon last year.
by Peter Lorre January 12, 2010
Get the mug
Get a Dharmageddon mug for your boyfriend Manley.