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Dharmageddon 

Term used to describe the big explosion at the end of Season 5 of the TV show "Lost" in which (apparently) everyone in the Dharma Initiative was destroyed by the detonation of a nuclear bomb.

Can also be used to refer to the upcoming Season Finale of "Lost" - the final end of the show which remains to be seen.
Dude, check out this blog, it's got spoilers on what happened to all the characters after the Dharmageddon last year.
Dharmageddon by Peter Lorre January 12, 2010
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pharmageddon 

the over-indulgence of pharmacueticals leading to the state of complete annihilation
ted's friends realised he'd reached pharmageddon, when they found him tits up in the gutter
pharmageddon by ed reese September 30, 2006

dramageddon 

A huge dramatic battle between two or more sides which will end in death until only one drama-army remains. Usually occurs on forums or IMs.
It was total dramageddon last night when Trixie found out Stacey had called her a skank behind her back.
dramageddon by Auau January 2, 2008

charmageddon 

A name given for the toilet paper hoarding that happened because of the COVID-19 coronavirus.
Charmageddon definition: The action of people buying out stores stock of toilet paper like they will never be able to buy toilet paper ever again.
charmageddon by anonymous April 25, 2020

harmageddon 

n. An escalating cascade of destruction initiated by a poorly thought-out action.

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If you touch the vena cava with that scalpel we will be here all night dealing with the erupting harmageddon.
harmageddon by gnostic3 December 27, 2014

harmageddon 

n. Confrontation in which hurt, physical or psychological, of Biblical proportion is inflicted one's opponent. Often used in jest or in sporting circumstances.

.................................
Yo! This weekend me and my crew are going to lay some harmageddon on you. You hear me? You will cry!

You know it's just a chess match, right?

Whatever dude. Just bring your tear-proof pawns.
harmageddon by gnostic 1 October 2, 2013

charmageddon 

n. A full-on irresistable James Francoesque charm storm of Biblical proportions.

.......................................................
Babe at four o'clock, but don't even bother. She is totally out of your league.

I'm going in. Don't wait up. No one can resist my charmageddon.

So I'll see you in five minutes?

Three.
charmageddon by gnostic 1 October 7, 2013