antsy pantsy Share definition Flag When you are just so antsy you cant wait to get into someones pants. You're antsy pantsy! Friend 1: "Have u hit that yet?" Friend 2: "No, fuck I'm getting antsy pantsy!" antsy pantsy by Heathalicious August 3, 2009 0 0 Get merch Get the antsy pantsy mug. Buy Now — $32.95 See more merch