A phrase that is never used
literally, but rather is
always a response to someone's laughing or poking fun at a problem the person has reason to be seriously concerned about.
Sometimes this reproach is, itself, used in a half-amused, bantering way.
"The
doctor said that I tested negative for cervical cancer, so I won't be at risk of infertility after all."
"Good to hear that it didn't
render your reproductive organs totally out of cervix."
"
Well, I'm glad you find this so amusing."