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To do a James is to have anal sex with three other men, You have to be a man to be able to do a James. Everyone also has do be covered in butter and it has to take place at 2:23 at night in an orphanage on a Monday and one of the men must be holding an aborted fetus.
Man, im gonna do a James tonight

damn man, you freaky
a James by M@llymoo1 March 20, 2022

A James Pullniga 

A James Pullniga is a unicellular organism that doesnt have the brain comprehension to get good results from any maths tests. Often is found in dank gutters and often takes the form of characters like "heimlich from bugs life" and franklin the turtle. If u manage to slay one of these creatures you will find estrogen pills fueling the existence of diabolical massive gyno milkers. A common trait of these animals are the red dots formed around its mouth (speculated to be herpes or aids from monkey). One of the only mouth breathing unicellular organisms in the universe.
Daddy Donohoe: Eww is that dumpster diving fat piece of shit 'A James Pullniga'
Ethan: It would appear so, it has massive gyno milkers and somehow male genitalia

A James Charles 

To pursue sexual activity with a person because they are of a different sexuality.
Jeffrey really pulled off a James Charles last night with my cousin who's a lesbian!

a james moment 

taking forever to take a turn in civ 6 and cause physical emotional and sexual pain.
you are taking forever this is actually a james moment
a james moment by djdeathblade December 17, 2023