Also a reference to the spirit of an antagonist, the drive behind opposition. If anything is against is getting in the way or holding you back, this is precisely the term that will cover this definition. Mainly used in frustration.
Joe: How are you doing man? I hear you're having a bad week.
Bill: Yeah, Yeşu is at it again. It seems I can't get anywhere.
Bill: Yeah, Yeşu is at it again. It seems I can't get anywhere.
by Jacobsen January 06, 2014