Intrusive thoughts of self-doubt and despair, often associated with depression or anxiety, that crawl into your brain and make it hard to focus on other things.
I was going to go to the party, but my brain-weasels were so bad that I couldn't deal with other people that evening.
Perhaps the most famous line from Cpt. Jean-Luc Picard in the STAR TREK: TNG episode "Datalore". Picard tells Wesley to shut up after he tries to warn the crew that they were actually talking to Lore, Data's evil twin. This also works when someone won't stop whining about something.
OTHER PERSON: You know, I wish you'd listen to me once in a while, because I happen to know...
YOU: Shut up, Wesley!
Used as an insult in the third installment of the Harry Potter series, Harry Potter and the Prisoner of Azkaban.
"You two shopping for your new dream home? Bit grand for you, isn't it, Weaselbee? Don't your family all sleep in... one room? " Draco as Ron is looking at the Shrieking Shack with Hermione.
An annoying and obnoxious individual. Someone who thinks they know it all but are actually trash at whatever it is that they’re doing. Someone who brings animosity to every situation that they’re in.
While our lifespan is the number of years we will live, our healthspan is the number of healthy years we will have and our sexspan is is the number of years we will continue to be healthy enough to continue having an active sex life.
A lighthearted reaction upon receiving disappointing news of some sort. Usually something that isn't a particularly a big deal, esp. when it primarily affects someone else - sort of a mild schadenfreude. Sometimes doubled or tripled, and possibly said in a sing-songy voice for added comedic effect to imitate a muted trumpet, which is how the meme originated.