Verb. Sending a tweet or tweeting @someone more famous than yourself in hopes that they will re-tweet and make you famous for a few minutes in the twitter-verse. Opposite of 'down tweet' or "down tweeting".
A gathering of nerds attempting social contact, likely for the first time. Usually disintegrates into everyone running to the nearest computer to type to one another.
Tommy: Hey Jethro, quit playing WoW its time to meet some folks at the tweetup!
Jethro: Oh yeah I forgot about that, I can't wait to meet BigBootay421 at the tweetup, but first I need to slay this orc!