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Sam O'Nella 

The only white lad canonically able to say the n-word.
Guy 1: Hey, did you see the newest Sam O'Nella episode?
Guy 2: Yeah I heard that he said the n-word.
Sam O'Nella by Eel on Musk September 30, 2019

Sam O’Nella

The supreme overlord of [short] [YouTube] videos which educate you on random subjects.
Person1: Hey have you heard anything about new Sam O’Nella videos?
Person2: Nah, he’s probably busy with work or something. He’ll return one day.
Sam O’Nella by Sauce boi June 13, 2021

Sam O'Nella 

a learning channel way more funnier than any other youtuber you can't make me deny that
"Sam O'Nella is the funniest youtuber!"
or
"Yeah, I watch Sam O'Nella. How could you tell?"
Sam O'Nella by JYCFox April 8, 2022

sam'o'nella 

the pinnacle of learning, also slightly physcophatic, maybe schizophrenic?
Hey, remember that one sam'o'nella video with weird stuff lol? Anyway, wanna play FISH JENGA?

*heavy breathing*

PUT YOUR HANDS WHERE I CAN SEE THEM YOU SICK BASTARD!
sam'o'nella by thedoge09 January 11, 2023

Sam O’nella Academy 

A online YouTube academy that, unlike salmonella, will improve your body with delicious knowledge juice every 2-3 months to improve your brain
Human 1 “Man I just got an F on this test”
Human 2 “DUDE, I told you to watch Newest Video on the Sam O’nella Academy”

Sam O'Nella Academy 

A wise youtube channel . Perfect for studying history (ex. for a test)
Hey, I watched Sam O'Nella Academy last night... got an A on my test. Also Sigmund Freud was a pretty weird dude.