The abbr. of SHUT THE FUCK UP PLEASE. This is commonly used when used by a polite and very angry goody goody who cannot forget their manners, and involuntarily and accidentally adds please.
Ashley: lalalala
Jessica: STFU
Ashley: don't you mean STFUP?
Jessica: the hell is STFUP? STFUP?
Ashley: it means shut the fuck up please. jeez
Jessica: dork
It is a harsher version of the word stfu. It is as if u were telling someone to "stfu", but so much so that it is as if you were to uppercut them with it.
Man 1: HEY DUDE IM SO COOL!
Man 2: dude shutup.
Man 1: DUDE BUT IM SOOOOOO COOL!
Man 2: dude stfu!
Man 1: DUUUUUUUDE!!!! IM SOOOO COOL!!!!
Man 2: DUDE THATS IT!!! STFUPPERCUT!!!