S.I.S.A. 

Studying Induced Social Awkwardness - when the time spent studying in a group (or alone) leads to social awkward behavior. These include but are not limited to laughing inappropriately, juvenile humor, and interactions that are abnormal at best.

He asked me how to get to the library. I forgot where it was. I had just left the library. Such S.I.S.A

She just changed her profile picture to be the cover of a book authored by a guys named Funk and Seamon... epic S.I.S.A.

Girl: "Hey, wanna come over later to, ummm, study"
Guy" "Do you mean sex?"
Girl: "Oh, God no, sorry, I momentarily forgot the word "study" - I didn't mean to suggest, no, i mean, not that I wouldn't be into it. Oh, God. Um, so, does 11 work?"
Guy: "S.I.S.A... i get it. I'll bring my Funk & Seamon study guide."

S.I.S.A. by eg$ May 21, 2011

S.I.S.A.S.B. 

This is an acronym for Shrek Is Such A Shrexy Beast

"Ooh," Jeofvubhs said, "look over there! It's Shrek!"
"S.I.S.A.S.B. right?" inquired Inafjbvashbf

S.I.S.A.S.B. by Le Shrek June 12, 2020

L.I.S.A. 

L = Logical
I = Intelligent
S = System
A = Administration

This individual only communicates through email, her existence is questionable, possibly a software system.

"Yo man can you run this by the L.I.S.A.?"
"I heard she's not even a real person"
"Swerve"

L.I.S.A. by TrapPharaohRogerBrown September 14, 2018

D I S A S T E R

Something said by a pro gamer

D I S A S T E R

-sebee

D I S A S T E R by AAAAAAAAAAAAAAAAAAAAAE October 20, 2022

i.s.a.f.r.i.l. 

this stands for..... "i'm such a f**king retarded idiotic loser! it is pronounced eye-is-a-frill.
also i.s.f.r - i'm so f**king retarded.

emily: aghhh!!
jake: sup??
emily: i.s.a.f.r.i.l......i've done it all wrong ill have to start over!!!

i.s.a.f.r.i.l. by Tango_Whore November 29, 2005

i s a t o p

i’m sick and tired of people

hey john use i s a t o p in a sentence

john: i’m sick and tired of people

i s a t o p by noyb._ May 15, 2020

C.I.S.A.T

Can I suck a tit?

Hey C.I.S.A.T

C.I.S.A.T by El.loco.fiki December 7, 2021