S.T.F.U. 

An abbreviated form of:

Shut The Fuck Up

Often used in the popular internet comic "Little Gamers" and on internet message board and chat rooms across the nation.

The Sims is teh suxorz.
S.T.F.U!!!!11

S.T.F.U. by molly November 15, 2003

S.T.F.U. 

Shut The Fuck Up.

The stupid bitch wouldn't STFU so I back handed her one.

S.T.F.U. by Sean October 25, 2003

S.T.F.U

SHUT THE FUCK UP

DUDE, S.T.F.U BEFORE I SHOT YOUR DUMB ASS!

S.T.F.U by * BOO - BOO * August 4, 2008

S.T.F.U.Y.D.W.

meaning: shut the fuck up you dirty whore

on instant messenger
bob: sally you have the nicest ass in the world
sally: S.T.F.U.Y.D.W.

S.T.F.U.Y.D.W. by waazzaabaaa January 26, 2006

S.T.F.U.Y.U.P.B 

Shut the fuck up you ugly piggly bitch

Hey S.T.F.U.Y.U.P.B

S.T.F.U.Y.U.P.B by Thebeareddragonteen August 2, 2020

s.t.f.u.y.p.o.s.

an aggresive term used mainly online and for texting meaning Shut The Fuck Up You Piece Of Shit!

after multiple text messges, the girl became annoyed and texted the sender back, saying "S.T.F.U.Y.P.O.S.!"

s.t.f.u.y.p.o.s. by Cornelius B. April 12, 2008

s.t.f.u.a.c.s.t.d 

bitch! “shut the fuck up and come suck this dick”

-lemme c&m in yo mouth😈😈

s.t.f.u.a.c.s.t.d

s.t.f.u.a.c.s.t.d by Yo mammy 😘 April 6, 2023