( 2-phenylethan-1-amine),
2- phenethylamine, β-PEA, PEA or phenylethylamine is a trace amine that is both endogenously and exogenously used .
In the CNS, It's natural purposes include VMAT2
inhibition and TAAR1 agonism to release dopamine, a substited phenethylamine with hydroxy groups on R 3 and 4.
Dopamine (especially D1 receptors in NAc) is involved in focus and reward.
People with ADHD have both lower levels of phenethylamine and dopamine in their brain.
Phenethylamine does exist in
chocolate. However it will not cause effects.
Naturally, orally ingested phenethylamine will not work due to the fact it's quickly metabolized by MAO B and then ALDH into phenyl acetic acid and leaves with urine.
However, ingestion of a MAOI B will cause ingested phenethylamine to travel directly into the CNS.
This will cause
the person to feel Intense stimulation and strong euphoria .
Phenethylamine can be both legally bought as freebase (
yellowish oil) and HCL (crystals).
Supplements of phenethylamine are
Substituted phenethylamines are molucles that have the base phenethylamine structure but with hydrogen atoms switched to different groups