A classification of chemical compounds, most of which are psychoactive drugs. Beta-Phenethylamine is neurotransmitter in the brain, and it is believed to be the body's natural version of amphetamine.
Some drugs that fall into the phenethylamine classification include all amphetamines (as well as methylphenidate), ephedrine, designer hallucinogens (2C-B, 2C-I etc.), mescaline, bupropion (Wellbutrin), and venlafaxine (Effexor), as well as the amino acids (D/L)Phenylalanine and L-Tyrosine.

Many (if not all) hallucinogenic phenethylamines are mentioned in the book PiHKAL (Phenethylamines i Have Known And Loved) by Dr. Alexander Shulgin and Ann Shulgin.
Dan: How exactly does Wellbutrin work as an apetite supressant?
Paul: Well, technically Wellbutrin is a phenethylamine and an amphetamine, so it blocks the reuptake of dopamine to curve your apetite.
by Patrick Sibley May 11, 2007
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A fantastic substance usually ingested in order to recieve a visual, spiritual trip. Effects typically set in after an hour or so of ingestion.
That San Pedro cactus sure stinks of 3,4,5-trimethoxy-ß-phenethylamine. Good mescaline there.
by Bill Billsworth October 28, 2003
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( 2-phenylethan-1-amine),
2- phenethylamine, β-PEA, PEA or phenylethylamine is a trace amine that is both endogenously and exogenously used .

In the CNS, It's natural purposes include VMAT2 inhibition and TAAR1 agonism to release dopamine, a substited phenethylamine with hydroxy groups on R 3 and 4.

Dopamine (especially D1 receptors in NAc) is involved in focus and reward.

People with ADHD have both lower levels of phenethylamine and dopamine in their brain.

Phenethylamine does exist in chocolate. However it will not cause effects.

Naturally, orally ingested phenethylamine will not work due to the fact it's quickly metabolized by MAO B and then ALDH into phenyl acetic acid and leaves with urine.

However, ingestion of a MAOI B will cause ingested phenethylamine to travel directly into the CNS.

This will cause the person to feel Intense stimulation and strong euphoria .

Phenethylamine can be both legally bought as freebase ( yellowish oil) and HCL (crystals).

Supplements of phenethylamine are

Substituted phenethylamines are molucles that have the base phenethylamine structure but with hydrogen atoms switched to different groups
Person 1: what are some examples of substituted phenethylamines ?

Person 2: adrenaline, amphetamine, MDMA, DOM.
by Acetone_professor_420 February 28, 2023
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