Making poopies refers to the act of taking a dump or taking a shit. This is the process of emitting fecal matter out of one's posterior orifice. I don't know why the term: 'taking a shit' caught on, since you're actually 'leaving' a shit'. Making poopies can be a means of describing your current situation or that of someone or something else. This expression can be used in differing tense's as given in the examples below.
Honey, you're not gonna believe this, but I have to make poopies.
Hey Louie, where's the poker dealer? Oh, he's in the shitter out back making poopies
another term for a station wagon, mini-van, or any other kind of vehicle that is targeted at the "family" demographic(also M.A.V.)
"Tactical advantages aside, the M.A.V. is top of the line for the holy warrior troop transport manufactured by the Church of Latter Day Saints Military Industrial Complex. Also great for family trips...to heathen lands."
12 step recovery jargon referring to someone new who talks about how great life is, now that they'resober. Usually meaning that the person is out of touch with reality.
The new guy seems pretty happy for a dude who has no job, no money and no family. He must be on a pink cloud.