Laughing My God Damn Ass Off. Based off of LMAO which means Laughing My Ass Off. Can also be used after ROTF to make ROTFLMGDAO (Rolling On The Floor Laughing My God Damn Ass Off.)
D00d 1: Yo, my homie Joe got his dick in a cast because he fell off the roof working on our dish!
D00d 2: LMGDAO!!!
While our lifespan is the number of years we will live, our healthspan is the number of healthy years we will have and our sexspan is is the number of years we will continue to be healthy enough to continue having an active sex life.
A lighthearted reaction upon receiving disappointing news of some sort. Usually something that isn't a particularly a big deal, esp. when it primarily affects someone else - sort of a mild schadenfreude. Sometimes doubled or tripled, and possibly said in a sing-songy voice for added comedic effect to imitate a muted trumpet, which is how the meme originated.