L's syndrome 

When you muck up real bad, and look like an idiot. An undeniable idiot in front of many people and all they can do is give you that look, the "what the fuck!?" look. The 'damn this kid's a dumb ass look". Too stupid to function...

Teacher: Ian, name the world's largest country?
Ian: Ahhhh...Popeyes chicken..?
Teacher: (The what the fuck did he just say look)
Class: (damn, this kid is stupid look)

Diagnosis: L's syndrome

L's syndrome by simonJeff June 12, 2011

O.L.S Old Lady Syndrome

a condition where you feel a compulsive need to turn down party invites and/or any other happy event that involves drinking

jay: Hey anthony, come over and let's drink some wine.

anthony: I'm sorry I can't. My booty is very saggy and sticky today. I can't get up my sofa.

jay: You need intervention! That's a sign of O.L.S Old Lady Syndrome.

O.L.S Old Lady Syndrome by jiggabuff December 5, 2011

l.t.f.b.s syndrome 

LOW TOLERANCE FOR BULL SHIT SYNDROME

Yes Sir your honer I was going to show up for the hearing last month for your hearing but my L.T.F.B.S SYNDROME WAS REALLY acting up everytime I tried to come in.

l.t.f.b.s syndrome by markantwhite August 23, 2015

Little Person Syndrome(L.P.S.)

Syndrome caused by an inferiority complex usually directed at stature or height. In women this may cause a variety of problems from "Bitchy-ness" to the urge to stand on large objects in order to feel some sense of "dominance" over others. Calling a woman who suffers from L.P.S. "tall" is a big compliment and will make them feel good about themselves. In men the problems multiply; men, already having an aggregation of complex's pertaining to their own inferiorities, become arrogant little fucks, who buy big trucks, and treat people like shit.

This syndrome is similar to L.M.S. or Little Man Syndrome, which is an inferiority with the size of ones own Male reproductive organ.

"Man that girl suffers from L.P.S. real bad she's just being a bitch to everyone."

"E.H.(hahah) is trippin', must be the L.P.S."

Little Person Syndrome(L.P.S.)

Little Person Syndrome(L.P.S.) by Long14 January 9, 2012

Lazy Face Syndrome [L.F.S.] 

The often recurring condition in which the state of one's face appears to feel as if it is "lazy," and/or "droopy" due to their current state of being stoned.

It could also be described as the condition of lacking initiative and motivation to move.

Man, Bob sure is suffering from a serious case of Lazy Face Syndrome L.F.S., he has been sitting in that chair doing nothing and drifting off into space this whole party.

Lazy Face Syndrome [L.F.S.] by TheSmokeBloke August 15, 2008

Annoying Little Brother Syndrome (A.L.B.S) 

Always at least a second child.
Usually tattles
Constantly steals the spotlight
Gets blamed by all older siblings

You know I'd like to go to the club, but my super Annoying Little Brother has some kind of Syndrome or something. I can't get over how whinny he is, and he's such a little snitch, he'll just tell my mom or dad. Stupid Annoying Little Brother Syndrome (A.L.B.S)

Annoying Little Brother Syndrome (A.L.B.S) by AUnknownSeaUrchin December 13, 2023

l.e.m.u.r.s. syndrome 

L: Long-term
E: Excessive
M: Masturbation to
U: Under-aged
R: Ripe
S: Sex

(REAL DISEASE)

I just got diagnosed with l.e.m.u.r.s. syndrome, so my mom can't be mad.

l.e.m.u.r.s. syndrome by cornjulio April 21, 2011