1.to make one angry specialy by bitching and not Shuting the fuck up.
2. to be made uncomfrotable becuase of a rash thats itchy because your dirty.
Example 1.
dude 1. wtf is wrong with jerry?
dude 2. he is angry cuase his boss irritated the fuck out of him earlier.
Example 2.
chick 1. like what are you doing?
Chick 2. i like have this rash thats irritating me and.
Chick 1. like ewwww you have aids.
by Sahara Desert December 17, 2008
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people that wont stop talking about stupid shit even when you are obviously uninterested in anything they have to say
Ed Benditt is so irritating,.. he kept talking on and on and on and i didnt hear a word he said neither was i responding but he just kept talking
by Tee-Dizz July 13, 2006
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A state of being at which you are ready to punch the next person who fucks with you in the face.
Person 1: Bitch don't fuck with me right now, I'm so irritated.

Person 2: Those are women's jeans.
Person 1: Square up bud.
by Anon.myous November 08, 2016
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shortened version of irritation:

feelings of irritation.. a scratchy annoyance.. like mild diarrhoea..
"you're giving me the irrits"
by Hannah Sheppard January 08, 2004
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Easily annoyed or angered. Cranky or grumpy. Cross, bad-tempered.
Sarah Good was called to testify. The irritable beggar rarely went to church and often muttered under her breath when she was denied food or shelter; she was an easy target for accusations of witchcraft.
by Lorelili August 05, 2011
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