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One answer to the question, "Is that person a whore". Meaning "ho for sure".
Frank: Is Debbie a whore?

Mike: She's a hofosho.
hofosho by Batost March 11, 2008
A woman who likes to get completely hammered at the bar and is willing to go home with any guy!
Hey look at that chick doing shots over there, shes a hofosho!
hofosho by Berg04 January 2, 2007
A website containing pictures of girls that dress sluty but still have their clothes on.
Antonio: What the fuck r u doing?!
Drew: Chill, I'm on Hofosho. They have shirts on!
Antonio: That's it! (cold cocked on the head)
Hofosho by Dhawk July 4, 2007
girl who doesnt know how to make people laugh
"Nat, you're a hofosho and you're really not funny"
hofosho by Natalosh March 13, 2008

Ho Fasho 

/ho-fah-sho/
Whore for sure; A promiscuous or adulterous woman
She’s a ho fasho. She’s had sex with like, everyone.
Ho Fasho by SiL3Nt J September 8, 2023