1. A man who acts like "a woman" by demonstrating typically female characteristics.
2. A woman (i.e., a lesbian) who dresses like a man.
Elgin was acting so passive-aggressive and manipulative, he was being a real cunt in men's clothing.
Betty, the bull dyke, just stepped out of the Men's Wearhouse in a new wool suit, looking just like a cunt in men's clothing.
An especially offensive thing to call someone, especially a dude. Technically it refers to the dark clots that sometimes work their way out early in a chick's period. If you don't believe me, ask a chick.