Chromosomite 

The Chromosomite is a word to define someone that has an Extra Chromosome/Was born with an Extra Chromosome, such as people with Trisomy. (Down Syndrome)

Look at this guy over there, he sure look like a Chromosomite!

Chromosomite by Saarlan December 19, 2019

Chromosomia

A dangerous, potentially contagious illness. The symptoms include, but are not limited to:

-Wearing plaid shirts and glasses
-Anime obssesion
-0 social skills
-Lowkey sexism
-Superiority complex
-Hating mainstream music
-Exclusively interested in math and IT
-Unusual fetishes and sexual deviance
-Using emojis like xD, :D, :P and =) even in professional settings
-Using Reddit OR using 4chan and hating Reddit

In severe cases, a person defined as a chromosome might have long hair, have incoherent speech and have stalker tendencies. Or be an incel.

Example 1

Guy1: Aw man, this dude is using xD even in emails to his boss.

Guy2: Shit, might be a severe case of chromosomia.

Example 2

Guy1: Man, this dude is such a chromosome.
Guy2: Right! He's always wearing plaid shirts and talking about how he has such a big brain.

Chromosomia by chromohunter69 October 1, 2020

Chromosome powerplay 

Meaning you have an extra set of chromosomes. Nice way of calling someone a retard. Powerplay is a man-up scenario in sports, mostly from opposing team serving a penalty.

Person 1: "Wow, that guy is a moron."

Person 2: "Yeah, they must have a chromosome powerplay going on."

Chromosome powerplay by M_Dubz152 June 6, 2023

chromosome thief

(n). One who steals another's chromosomes to bring about autism, down syndrome, etc.

Look out, there's a chromosome thief coming towards us!

chromosome thief by _thememeprophet_ February 27, 2017

extra chromosome 

What makes a Down's Syndrome person how they are.

Timmy has an extra chromosome, that's why he goes to special school.

extra chromosome by Ray Flynn May 20, 2005

sex-chromosome anomaly 

This is a genetic abnormality that does not have to do with being gay, lesbian, etc. This abnormality is seen when the XY or XX chromosomes have more than the usual X and Ys. This can lead to infertility in males or females and physical traits not normally of that sex. For more information, check the page on biology. about. com about Sex Chromosome Abnormalities.

Sex-chromosome anomaly (abnormalities) are a result of chromosome mutations.

sex-chromosome anomaly by Phoebe Jones May 11, 2016

smoke yourself a spare chromosome 

To smoke weed until you're retarded, as Down's Syndrome is cause by the presence of an extra chromosome.

Chich : We finished a quarter ounce between us last night, man. I think I'm still kinda faced.

Chung : Shit son, you don't watch out you'll smoke yourself a spare chromosome.

smoke yourself a spare chromosome by Parhelion February 22, 2009