Pronoun used interchangably with both he and she; the substitute of "them" when a speaker doesn't know the gender of referral.

Also 'e and simply "e" in formal writing

Derived from lazy people who can't even pronounce the first consonant in words.
Is that person in the lunch line a guy or a girl? And what is 'E buying?
by squidgetex May 5, 2009
the sound an ambulance makes as it leaves your neighborhood.
The ambulance carrying my cousin went E-e-E-e-EE-e as it sped through the night. It's too bad he's in a chair now.
by T-Dog Jenkins July 16, 2005
That name is the most common rap name of 2018. For example, FEFE, ZEZE.
Here are the *E*E song names:

6ix9ine: FEFE, BEBE, KEKE
Kodak Black: ZEZE
Michael Jackson: HEHE
R. Kelly: PEPE
Bobby Shmurda: FREEME
by Ong fr moment November 23, 2018
"Escape and Evasion"

A term used mostly by the military. Meaning: To get away from the badguys, and hide.
Those gangmembers thought that *I* was the one who took their drugs! They came after me, and I had to go into E&E mode...
by Whind Soull May 13, 2005
It is a smiley. the 'e' are the eyes, and the ',' is the mouth. it can represent anticipation, surprise and amusement ect. A similar smiley that can be used instead: e.e
User 1: Lol, you just said that you were a noob.

User 2: I lied e,e

User 1: Damn!, you had me there.
by glustora October 15, 2011
An emoticon suspecting something fishy or suspicious. The two 'e's are meant to be squinted eyes and the dash (-) a mouth. Often used when texting or talking to someone online.
Person #1: psh i didnt do that why would you accuse me of that? :c
Person #2: Alright... I'm keeping my eyes on you e-e
by GiveMeBackMyName August 31, 2013
When u can’t think of anything to say or respond just say e
E
by Rudey2 February 14, 2019