wyke-syke Share definition Flag A more powerful version of the term "syke", only to be used for case of extreme irony. Hails from San Diego. I can't wait to eat this popcorn. Wyke-syke, I have no teeth. wyke-syke by beineken May 3, 2012 0 0 Get merch Get the wyke-syke mug. Buy Now — $32.95 See more merch
