The kind of laugh that sounds like a man that is dying because he smokes too much.
After her friend sent her a meme, she started wheezing of laughter and her parents came up to her room because they thought she was dying but no, she was just wheezing.
Short-hand for the word floccinaucinihilipilification, meaning the estimation of something as valueless (encountered mainly as an example of one of the longest words in the English language).