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1) In street culture influenced by Chicago gang culture and Drill Music, "we up" is an oblique reference to the score. The score is a record of gang members slain by their rivals. Each death demands reprisal. Literally, then, to be "up" means that your side has killed more of their side than they have of yours; you have a net positive account of bodies.

2) To be "up" also means to be solvent, to have drugs to sell, and to be powerful, on point, in the sense of "on top." This wider usage is probably because the direction "up" usually corresponds with positivity, happiness, and thought in our culture, according to George Lakoff.
"You must be trippin' if you really think that they up"
- G Fredo

"Have you any refined cocaine in your possession, which you are willing to exchange for currency, later today?"

"Yeah, we up."
we up by The Grown-Up August 9, 2020
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We up fr 

Use this phrase when you’re winning at life.
Brooooo, shawty wants me soo bad.

I know bro, and my girl and me are back together

“We up fr” right now
We up fr by marinoa21 September 24, 2022

We up fr 

“We up fr” is said when a mf is so low in life, the only way to make himself feel better is by gaslighting himself into thinking he’s “up”
Guy 2: yo how did your date go?

Guy: she stood me up, who cares her loss, we up fr
We up fr by Pooppants69420 January 23, 2023

started from the bottom now we way up

he's the nigga driving fast and also _extendo_ boyfriend
-started from the bottom now we way up
-dude shut the fuck up

we going up streaks 

basically when something exciting is about to happen.
im getting a new phone, we going up streaks
we going up streaks by yikes dude January 5, 2019

we dont switch up we dont fold 

Never switching up or giving up on the homies, to do what ever it takes
Aye yo mike left me to die

Damn what happened to we dont switch up we dont fold

Let’s go we pull up

When gangs in Da hood when they pull up.
Gang Leader: Yeah finally we own this building in Da hood.
Everyone in the gang: Let’s go we pull up
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I had a trucker's tan after driving for 10 straight hours on a sunny day.
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Origin of the word is unknown. Started sometime in World War 2. Given the typical evolution of British slang, could easily have started because what these experts did was confusing or “baffling” to the common person.
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