This is a sly reference to and synonym for the penis or cock. For males adding the penis to the 10 fingers and 10 toes makes 21 appendages. Use this if you want to sound intelligent or don't want stupid or younger people to know what you are talking about.
I'm in the process of writing an epic poem about the love between me and my twenty-first appendage.
Someone who jumps from one relationship immediately into another one.
Serial monogamists can not stand to be alone and often suffer from vast commitment and insecurity issues.
Because they jump into relationships immediately after the previous one has ended, serial monogamists typically don't take the time to reflect on their behavior or why their previous relationships failed; thus, they end up making the same relationship mistakes over and over again.
Person 1: Damn, Dustin already has a new girlfriend?! It's only been two weeks since he broke up with his fiance! I think he's a sociopath.