spice cream Share definition Flag Superheated, ultra-painful liquid feces brought on by ingesting spicy food and/or cheap alcohol. "Man, I was in tears on the bowl for an hour from the Spice Cream the wings and beer gave me." spice cream by Whitey McGee September 22, 2007 0 0 Get merch Get the spice cream mug. Buy Now — $32.95 See more merch