A person who smokes an insane amount of meth- this person has lost all sense of reality and morality. They would probably do something like fight shadow monsters in their attic.
Or it can be used as a verb-
to be spindoodlegoostered
That painting is so splendoodle, I'm drowing in torrents of my own tears, I love it so much, argh the pain! Must tear my gaze away; it's burning my eye-sockets with it's maddening beauty and radness.