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A common misspelling of the word "plague" usually used by people who are either too ignorant to know the difference or by people who became too eager to type the letter "u" that they accidentally misspelled plague.
He was overly stimulated by the thought of typing the letter 'u' that he wrote plauge instead of plague.

The Black Plague: a historical event in which many people died of an infectious illness carried by rats. The Black Plague has nothing to do with race...as far as I know.
Plauge by pseudonym_can_be_blank November 20, 2013
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(plawsh) also (Plawj), n. An epidemic that kills people with little sign or symptons before the disease becomes lethal.
Anthrax, is considered to be a plauge by many because in the period in which it can be treated, it appears only as a common cold.
Plauge by Bizzoris April 16, 2006
Will eat your bones

(Definitely not a plague)
Oh no, the plauge is coming.
Plauge by GoodTimesTacos June 14, 2021
a misspelling of the word "plague" from the officalverse
Plague-Offical: "Fine, he dies of the plauge"

Boobonic Plauge 

When a woman of low morals goes and gets three or four breast implants in a row. Considered distasteful.
Looks like Pamela Anderson's got that Boobonic Plauge...
Yeah, and she's Canadian!
Boobonic Plauge by Marty Potter September 6, 2005

Black Plauge 

When a female (of non-African origin) is avidly attracted to males of the black persuasion.
Ugh, Amanda has caught the Black Plauge! Hopefully it's just a phase....
Black Plauge by PJoH7 July 25, 2012

Lesbionic Plauge 

The disease that converts women into Lesbians and men into women and the Lesbians. Scientific name is the M1N93 Virus.
The Lesbionic Plauge is sweeping across Europe and will soon reach the USA.
Lesbionic Plauge by Capper August 15, 2006